Role of serum trace elements magnesium, copper and zinc, level in Libyan patients with bronchial asthma

The present study compared the levels of serum Mg, Cu and Zn between the adult with asthma and healthy volunteer in order to evaluate the associations of these nutrients with asthmatic patients. Thirty-three adults patients of both (19 males, 14 females) with the median age 39 years with bronchial asthma, who were admitted by the Department of Pulmonary Diseases of Shat and Alkyfaya Hospitals, were included in the study. Thirty-three adult patients of diagnosed bronchial asthma of both sexes (19 males and 14 females) attending Pulmonary Diseases Care Unit at Shat and Alkyfaya Teaching Hospital in El-Beida and Benghazi Cities and 31 healthy volunteers (17 males, 14 females) were studies. A serum elements level was measured using atomic absorption spectroscopy technique at calibration mode.The results indicated that serum of Cu, Zn and Mg levels in male and female adults with asthma were significantly lower (P<0.001) in compared to healthy controls.On the basis of this study finding and those of other reports, trace elements deficiency may contribute to diets and diseases through its significant effects on the antioxidant enzymes’ functions, and decrease the antioxidant capacity in asthma. It seems that the estimation of serum or plasma trace elements may help in investigation of asthmatic disease in both males and females.